Quality control in advance of the usual final inspection: Inspection Applications

Seidenader's inspection applications are based on a consistent modular concept. Their process-optimized construction guarantees easy integration into new or existing production lines from many different manufacturers. Seidenader focuses on fulfilling the most demanding requirements in terms of reliability and quality and on ensuring customer satisfaction.

Industrial Vision Solutions

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Empty Container Inspection

Closure Integrity Inspection

Cross Contamination Inspection

Line Management Solutions

High-voltage inspection (HV)

Leak inspection of liquid-filled containers and check for pierced needle shields on syringes

Micro-cracks or pinholes in the sidewall, bottom or closure zone of liquid-filled containers, invisible to cameras, can be reliably detected using high voltage (HV). For this inspection, the inner surface of the container is wetted with the product and the container is conveyed past the electrodes at a small distance. A leak in the object leads to a reduction of the resistance and hence to an increase in the e electrical flow. A container with a measured current higher than a defined maximum will be rejected.

Typical high-voltage inspections are:

  • Tightness (HVLD = High Voltage Leak Detection), for ampules, cartridges, vials and syringes, filled with liquid, exhibiting a minimum conductivity of 1 μS/cm.
  • Pierced needle shield (HVNSI = High Voltage Needle Shield Inspection) for syringes.
  • HV syringe inspection - needle-up

Laser-based headspace analysis (HSA)

Leak inspection of lyo products

Headspace analysis using of TDLAS (Tunable Diode Laser Absorption Spectroscopy) is a spectroscopic method which enables 100% non-destructive inline inspection of pharmaceutical products using various criteria. A laser beam, which is tuned to specific wavelength coverage, passes the headspace of a container. A photo sensor receives the transmitted laser light; evaluation of the sensor signal supplies information about the composition of the gas inside the container.

When containers are sealed under positive or negative pressure, certain parameters of the headspace gas change if there are leaks. If such changes are detected, this indicates a leak. Depending on the version of the system, the absolute pressure or the water or oxygen partial pressure can be determined. In addition, the oxygen content in the headspace can be determined.

A typical HSA application is leak inspection of containers filled with lyophilized product and sealed under negative pressure.

More information

Find more information on inspection applications at the

Seidenader website

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